ABSTRACT NEW DISCOVORIES FOR THE REGENERATION OF DAMAGED NEURONS (Possible cures and relief for millions of people) Normally, neurons in the central nervous system (the brain and spinal cord) cannot regenerate injured nerve fibers, limiting people’s ability to recover from brain or spinal cord injuries. Repair of the central nervous system and restoration of voluntary motor activity through axonal re-growth has long been considered impossible in mammals. Over the last decade, numerous attempts proved disappointing overall.
While repair of the central nervous system has long been considered impossible have just developed some strategy in the past two years that could promote neuronal regeneration after injury 1. Regeneration of the corticospinal system- Restoring these axons is an essential step that in one day enabling patients to regain voluntary movement after spinal cord injury. 2. In the event of spinal injury or lesion, astrocytes proteins isolate the damaged neuron to prevent interference with the operation of the central nervous system. . With further research, scientist hope to work towards identifying ways in which Schwann cells and c-Jun could be used to repair the spinal cord, 4. The biomimetic polymers- This technique would use a biodegradable polymer containing a chemical group that mimics the neurotransmitter acetylcholine to spur the growth of neurites, and then it would guide the growth of the regenerating nerve. 5. Damaged nerves are regenerated by silencing natural growth inhibitors in neurons called PTEN and TSC1 by using genetic techniques. . Bone Marrow Cell Transplants, containing adult stem cells are protected and nourished with bio-engineered materials which then successfully help to regenerate damaged nerves. The research may provide an important step in developing artificial nerves. 7. Master regulator found for regenerating nerve fiber in live animals that an enzyme known as Mst3b is identified as essential for regenerating damaged axons in a live animal model, in both the peripheral and central nervous systems.